INTEGRATIVE NEUROPHYSIOLOGY GROUP

Integrative Neurophysiology

The Integrative Neurophysiology group aims to discover emergent phenomena from neuronal systems in the brain and the spinal cord.

In particular, we analyze the electrical and hemodynamic activity of populations of neurons from the cerebral cortex, cerebellum, brainstem, and spinal cord. We integrate the study of sensory and motor systems, including neuronal systems involved in cognitive processes. We also study the complex language between neurons that includes random signaling called “neuronal noise.”

Our findings will help to generate new knowledge about fundamental mechanisms of perception, motor action, and cognition, in functional and pathological states. They also will help to design advanced prosthetic devices to augment the functional capabilities in subjects with neuronal disorders in the brain and spinal cord. 

Our experiments are performed in acute or chronic preparations in anesthetized or decerebrate animals, but also noninvasively in the human.

 

Our Methods and Heuristic Techniques

First, we explore new questions noninvasively in the human brain or the spinal cord, and then we come back to the animal preparations to examine physiological mechanisms or vice versa.

We employ emerging technologies that are perceived as capable of changing the status quo in the studies of the spinal cord or the brain functions. We also develop new neurotechnologies to open new questions in the field of emergent phenomena from the studied neuronal systems.

Some of these neurotechnologies are Optogenetics, Multielectrode Recording, Microelectromechanical Systems (MEMS), functional NIRS, transcranial random noise stimulation (tRNS), transcranial magnetic stimulation (TMS).

 

Emergent phenomena from which our group is pioneer in the Integrative-Neurophysiology field

  • The internal stochastic resonance phenomenon in the nervous system
  • The multisensory stochastic resonance phenomenon
  • The internal multisensory stochastic resonance phenomenon
  • The phenomenon of traveling waves in the spinal cord during a rhythmical motor task
  • The post-scratching locomotion phenomenon
  • The phenomenon of pre-movement electrical potentials in unconscious decerebrate animals

 

New neurotechnologies that we developed

Optogenetic noise photostimulation (ONPS), Spinal Cord Multielectrode Matrix (SCMM), Device for detection of EEG traveling waves in the human brain, Multisensory Stimulation Device (MSD).

People


Research Team

Elias Manjarrez Ph.D.

Elias Manjarrez received the B.Sc. degree in physics, the M.Sc. degree in physiology from Benemérita Universidad Autónoma de Puebla, México, and the Ph.D. degree in neuroscience from CINVESTAV-IPN, México, in 2000. He was invited professor at the Neurological Clinic, Albert-Ludwigs University of Freiburg, Germany.

Since 2001, he has been with the Institute of Physiology, Benemérita Universidad Autónoma de Puebla, México, where he is an Interdisciplinary Research Scientist and Head of the Laboratory in Integrative Neurophysiology. His areas of interest include integrative neurophysiology, stochastic resonance, traveling waves in the brain and spinal cord, spinal central pattern generators, neurophysics, mathematical modeling and biomedical applications of sensors and actuators.

Dr. Manjarrez is member of the National System of Researchers Level 3 and the Mexican Academy of Science. He obtained some competitive grants from CONACYT as “Fronteras de la Ciencia” https://www.conacyt.gob.mx/index.php/el-conacyt/desarrollo-cientifico/fronteras-de-la-ciencia and “Proyecto de Infraestructura científica y tecnológica” https://www.conacyt.gob.mx/index.php/fondos-y-apoyos/apoyos-infraestructura, and the Cátedra Marcos Moshinsky http://www.fmm.fisica.unam.mx/

 

Contact

eliasmanjarrez@gmail.com

elias.manjarrez@correo.buap.mx

+5222 2295500 Ext 7326

 

Overview

Nayeli Huidobro Ph.D.

Nayeli Huidobro received her degree in Biomedical Research from Benemérita Universidad Autónoma de Puebla in 2010. Later, she obtained her Masters in Science in 2013 in Physiological Sciences from the Institute of Physiology at the same university, and her Ph. D. in 2018. Currently, she is collaborating with Prof. Elias Manjarrez. Huidobro’s research interests are motor control, cerebellar somatotopy, multisensory integration, optogenetics, stochastic resonance, and statistics.

Ignacio Méndez-Balbuena Ph.D.

Ignacio Méndez-Balbuena received the B.Sc. degree in physics, the M.Sc. degree in physiological sciences from Benemérita Universidad Autónoma de Puebla, México, and the Ph.D. in physiology from Institute of Physiology, Benemérita Universidad Autónoma de Puebla, México, 2004. Post-doctorate at the Laboratory for Motor Control, Neurological Clinic, Albert-Ludwigs University of Freiburg, Germany. Currently he is Professor of the Faculty of Psychology, Benemérita Universidad Autónoma de Puebla. He is mainly interested in the development of paradigms related to experimental psycho-physiology.

Dr. Méndez Balbuena is member of the National System of Researchers Level 1.

Amira del Rayo Flores-Urbina Ph.D.

Amira del Rayo Flores received her degree in Psychology from Benemérita Universidad Autónoma de Puebla. Later, she obtained her Masters in Science in Physiological Sciences from the Institute of Physiology at the same university, and her Ph. D. degree in neuroscience from CINVESTAV-IPN, México, in 1999.

Since 2000, she has been with the Institute of Physiology, Benemérita Universidad Autónoma de Puebla, México, where she is an Interdisciplinary Research Scientist and Head of the Neurobiology Laboratory. Her areas of interest include synaptic transmission between hair cells and vestibular primary afferents, neuro development of the chicken auditory system, stochastic resonance mechanisms in synaptic transmission and integrative neurophysiology.

Dra. Flores is member of the National System of Researchers Level 2.

Former Member

Roberto Meza

Biologist Roberto Meza-Andrade obtained his degree in Biology from Benemérita Universidad Autónoma de Puebla in 2007. Subsequently, he attended the Institute of Neuroethology at University of Veracruz and earned his master’s degree in 2014. Currently, he is a PhD candidate at the Institute of Physiology of the University of Puebla. Roberto Meza is mainly interested in the central control of respiration, respiratory physiology, central pattern generators, and motor control. His PhD thesis was related to the functional relationship between the central patterns generators of scratching and respiration, and the use of new optical technologies to detect BOLD signals in the cat spinal cord during scratching.

Abraham Méndez Fernández

Abraham Méndez Fernández, received his Bachelor degree in Biomedical Research from Benemérita Universidad Autónoma de Puebla, in 2016. He is ending his Master in Science Thesis about the pehnomenon of bistability in dorsal horn neurons from the cat spinal cord. 

Ivan Zea, Visiting researcher

Ivan Zea, former Research Technician at Duke University Medical Center. He received his bachelor’s degree in Genomic Sciences from National Autonomous University of Mexico in 2015. Later on, he started working as a Research Technician with Miguel Nicolelis http://www.nicolelislab.net/ at Duke University exploring novel sensory modality representations in the rat’s primary cortices using a cortical prosthetic system. His main research interests are Brain Computer Interfaces, neuroengineering, data science, and machine learning.

Postdoctoral Fellows

Otto García Garibay Ph. D. Postdoctoral fellow

Otto García Garibay received the B.Sc. degree in Biomedicine and the M.Sc. degree in physiological sciences from Benemérita Universidad Autónoma de Puebla, México, and the Ph.D. in biomedical sciences from the Institute of Neurobiology from the Universidad Nacional Autónoma de México, Campus Juriquilla, México, 2018.

He is mainly interested in motor control, cognition and perception.  Currently he is working in the understanding of perceptual differences between individuals during cognitive tasks.

Dr. García Garibay is member of the National System of Researchers Level candidate.

PhD Students

Pedro Mabil

He received his bachelor’s degree in electronic engineering from technological institute of Veracruz, in 2013, his Master in Science in 2016 in Micro and nanosystems, from Institute of Micro and Nanotechnology, University of Veracruz. His PhD thesis examines the functional mechanisms of electrical and optical stimulation of pyramidal neurons from the rat somatosensory cortex. He employs electrical and optogenetic noise stimulation in in vivo and in vitro preparations of transgenic animals.

José Ángel De Luna Castruita MSc

De Luna Castruita achived a bachelor’s degree in Psychology from Universidad Autónoma de Ciudad Juárez, México in 2012, and a Master degree in Neuropsychological Diagnostic and Rehabilitation from Benemérita Universidad Autónoma de Puebla in 2018.  His research line employs cognitive event related potentials in subjects with cognitive impairment due to demyelinating diseases. He is focused to examine functional correlates between MRI and EEG in patients diagnosed with Multiple Sclerosis with high and low lesion load. Currently he is elaborating his PhD project based on new perceptual and cognitive EEG biomarkers of neuronal variability.

Master Students

Mayra Moreno

Mayra Moreno received her degree in physical therapy from Professional Institute in Therapies and Humanities in Puebla City, in 2015. Currently, Mayra is studying the masters in Physiological Sciences in the Institute of Physiology at Benemérita Universidad Autónoma de Puebla. She works with motor control of the locomotion and scratching.

Linda Victoria Lizarraga Cortes

Linda Victoria Lizarraga Cortes received her degree in Computer Science Engineering in 2016 at Benemérita Universidad Autónoma de Puebla. She is a full time student in the Physiological Science Master’s Degree Program at the same university since 2017. She made an internship at Dormunt University, Germany in 2018 in the laboratory of Dr. Ruge and Dr. Trenado. Victoria has expertise in programming languages such as MATLAB and C/C++, Networks and Data Bases.  She made an internship in 2018 at the iFADo institute in Dortmund, Germany. She is currently ending her master in science thesis, examining the somatosensory system plasticity after electrocortical stimulation.

Anai Gonzalez-Ramirez

Anai Gonzalez-Ramirez, BSc, received her degree in Biomedical Research from Benemérita Universidad Autónoma de Puebla, in 2017. She is currently studying her Masters in Science in Physiological Sciences at Institute of Physiology. She made an internship at Dormunt University, Germany in 2018 in the laboratory of Dr. Ruge and Dr. Trenado. Gonzalez-Ramirez currently is working in her MSc thesis examining neural variability in EEG evoked potentials in humans.

Jesús Jaime Romero Vaca

Jesús Jaime Romero Vaca, received his degree in Biology from Benemérita Universidad Autónoma de Puebla, in 2018. He is currently studying his Master in Physiological Sciences at Institute of Physiology. His thesis is related to the application of a new optical technology to detect changes in blood flow in the cat spinal cord.

Jorge Gutierrez

Jorge Gutierrez, received his degree in biomedical Research from Benemérita Universidad Autónoma de Puebla, in 2018. He is currently studying his Master in Physiological Sciences at Institute of Physiology. He is characterizing electrical activity of single neurons from the cat spinal cord associated with the phenomenon of spinal traveling waves during scratching and locomotion.

Bachelor Students

Hector Halin Carbajal Guevara.

Hector Halin Carbajal Guevara is a Bachelor student in Biomedical Research from Benemérita Universidad Autónoma de Puebla. Currently, he is collaborating with researchers from the Institute of Cellular Physiology from UNAM and BUAP. His BCh thesis is related to operant conditioning and electrophysiological recordings in transgenic mice during the application of optogenetic noise photostimulation.

 

Collaborative Network

International collaborations

 

 

 

National collaborations

 

 



Patents Granted

  • Patent granted by Mexican Institute of Industrial Property IMPI #351753, “Title: Trayectómetro de señales eléctricas cerebrales”. Patent granted from October 18th 2017 to September 28th 2032.
     
  • Patent granted by Mexican Institute of Industrial Property IMPI #357897, Title: Dispositivo neuromimético del dedo humano controlado por antiresonancia estocástica”. Patent granted from July 4th 2017 to September 28th 2032.
     
  • Patent granted by Mexican Institute of Industrial Property IMPI #359610, Title: Multielectrodo de superficie motorizado de 32 canales”. Patent granted from September 14th 2017 to September 28th 2032.

Publications

2020

Moreno-Castillo M, Meza R, Romero-Vaca J, Huidobro N, Méndez-Fernández A, Martínez-Castillo J, Mabil P, Flores A and Manjarrez E 

(2020) The Hemodynamic Mass Action of a Central Pattern Generator. Front. Neurosci. 14:38. doi: 10.3389/fnins.2020.00038

Méndez-Fernández A, Moreno-Castillo M, Huidobro N, Flores A, Manjarrez E

 (2020) Afterdischarges of Spinal Interneurons Following a Brief High-Frequency Stimulation of Ia Afferents in the Cat. Front Integr Neurosci. 13:75. doi: 10.3389/fnint.2019.00075

2019

Trenado C, González-Ramírez A, Lizárraga-Cortés V, Pedroarena Leal N, Manjarrez E, Ruge D. 

(2019) The Potential of Trial-by-Trial Variabilities of Ongoing-EEG, Evoked Potentials, Event Related Potentials and fMRI as Diagnostic Markers for Neuropsychiatric Disorders. Front Neurosci. 12:850. doi: 10.3389/fnins.2018.00850.

Meza R, Huidobro N, Moreno-Castillo M, Mendez-Fernandez A, Flores-Hernandez J, Flores A, Manjarrez E.

(2019) Resetting the Respiratory Rhythm with a Spinal Central Pattern Generator. 6(2). Pii: eNeuro 0116-19.2019. doi: 10.1523/eneuro.0116-19.2019

Remedios L, Mabil P, Flores-Hernández J, Torres-Ramírez O, Huidobro N, Castro G, Cervantes L, Tapia JA, De la Torre Valdovinos B, Manjarrez E (2019)

Effects of Short-Term Random Noise Electrical Stimulation on Dissociated Pyramidal Neurons from the Cerebral Cortex. Neuroscience. 404:371-386.

2018

Huidobro N, De la Torre-Valdovinos B, Mendez A, Treviño M, Arias-Carion O, Chavez F, Gutierrez R, Manjarrez E (2018).

Optogenetic noise-photostimulation on the brain increases somatosensory spike firing responses. Neurosci Lett. 664: 51-57.

Cuellar CA, De La Torre Valdovinos B, Huidobro N, Delgado-Lezama R, Ornelas-Kobayashi R, Manjarrez E (2018)

The Spinal Neurons Exhibit an ON-OFF and OFF-ON Firing Activity Around the Onset of Fictive Scratching Episodes in the Cat. Front Cell Neurosci. 12:68. doi: 10.3389/fncel.2018.00068.

Mendez-Balbuena I, Arrieta P, Huidobro N, Flores A, Lemuz-Lopez R, Trenado C, Manjarrez E (2018).

Augmenting EEG-global-coherence with auditory and visual noise: Multisensory internal stochastic resonance. Medicine (Baltimore). 97(35): e12008. doi: 10.1097/MD.0000000000012008.

2017

Huidobro N, Mendez-Fernandez A, Mendez-Balbuena I, Gutierrez R, Kristeva R, Manjarrez E (2017).

Brownian optogenetic-noise-photostimulation on the brain amplifies somatosensory-evoked field potentials. Front Neurosci. 11: 464. https://doi.org/10.3389/fnins.2017.00464

Ceballos-Villegas ME, Saldaña-Mena JJ, Gutierrez-Lozano AL, Sepúlveda-Cañamar J, Huidobro N, Manjarrez E, Lomeli J. (2017).

The complexity of H-wave amplitude fluctuations and their bilateral cross-covariance are modified according to the previous fitness history of young subjects under track training. Frontiers in human Neurosci. 11: 530

Canto-Bustos M, Loeza-Alcocer E, Cuellar CA, Osuna P, Elias-Viñas D, Granados-Soto V, Manjarrez E, Felix R, Delgado-Lezama R. (2017).

Tonically Active α5GABAA Receptors Reduce Motoneuron Excitability and Decrease the Monosynaptic Reflex. Front Cell Neurosci. 11:283.

2016

Franco LM, Beltrán JQ, Tapia JA, Ortiz F, Manjarrez E, Gutiérrez R (2016).

Differential frequency-dependent antidromic resonance of the Schaffer collaterals and mossy fibers. Brain Struct Funct. 221(4):1793-1807

Flores A, Manilla S, Huidobro N, De la Torre-Valdovinos B, Kristeva R, Mendez-Balbuena I, Galindo F, Treviño M, Manjarrez E (2016).

Stochastic resonance in the synaptic transmission between hair cells and vestibular afferents in development. Neuroscience. 322: 416-429.

Treviño M, De la Torre-Valdovinos B, Manjarrez E (2016).

Noise improves visual motion discrimination via a stochastic resonance-like phenomenon. Front Hum Neurosci. 10:  572.  http://dx.doi.org/10.3389/fnhum.2016.00572

2015

Mendez-Balbuena I, Huidobro N, Silva M, Flores A, Trenado C, Quintanar L, Arias Carrion O, Kristeva R, Manjarrez E (2015).

Effect of mechanical tactile noise on the amplitude of visual evoked potentials: Multisensory stochastic resonance. Journal of Neurophysiology. 114: 2132-2143.

Trejo A, Tapia JA, De la Torre Valdovinos B, Huidobro N, Flores G, Flores-Hernandez J, Flores A, Manjarrez E (2015).

Transition of pattern generation: The phenomenon of post-scratching locomotion. Neuroscience. 288: 156-166.

2014

Trenado C, Mikulic A, Manjarrez E, Mendez-Balbuena I, Schulte-Monting J, Huethe F, Hepp-Reymond MC, Kristeva R (2014).

Broad-band Gaussian noise is most effective in improving motor performance and is most pleasant. Frontiers in Human Neuroscience. 8: 22. http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00022/abstract

Cuellar CA, Trejo A, Linares P, Delgado-Lezama R, Jiménez-Estrada I, Abyazova LM, Baltina TV, Manjarrez E.(2014).

Spinal neurons bursting in phase with fictive scratching are not related to spontaneous cord dorsum potentials. Neuroscience. 266: 66-79

Trenado C, Mendez-Balbuena I, Manjarrez E, Huethe F, Schulte-Monting J, Feige B, Hepp-Reymond MC, Kristeva R (2014).

Enhanced corticomuscular coherence by external stochastic noise. Front. Hum. Neurosci. 8: 325. http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00325/abstract

Romero-Pimentel AL, Vazquez-Roque RA, Camacho-Abrego I, Hoffman KL, Linares P, Flores G, Manjarrez E (2014).

Histological correlates of N40 auditory evoked potentials in adult rats after neonatal ventral hippocampal lesion: animal model of schizophrenia. Schizophrenia Research. 159(2–3): 450–457.  doi:10.1016/j.schres.2014.09.009

Herrera-May AL, Tapia JA, Dominguez-Nicolas SM, Juarez-Aguirre R, Gutierrez-D EA, Flores A, Figueras E, Manjarrez E (2014).

Improved detection of magnetic signals by a MEMS sensor using stochastic resonance. PlosOne 9(10): e109534. doi:10.1371/journal.pone.0109534

Trenado C, Amtage F, Huethe F, Schulte-Monting J, Mendez-Balbuena I, Baker SN, Baker M, Hepp-Reymond MC, Manjarrez E, Kristeva R (2014).

Suppression of Enhanced Physiological Tremor via Stochastic Noise: Initial Observations. PlosOne 9(11): e112782. doi:10.1371/journal.pone.0112782

Martinez-Silva L, Manjarrez E, Gutierrez-Ospina G, Quevedo JN (2014).

Electrophysiological representation of scratching CPG activity in the cerebellum. PlosOne 9(10): e109936. doi:10.1371/journal.pone.0109936. http://www.ncbi.nlm.nih.gov/pubmed/25350378

2013

Kato H, Cuellar CA, Delgado-Lezama R, Rudomin P, Jimenez-Estrada I, Manjarrez E, Mirasso CR (2013).

Modeling zero-lag synchronization of dorsal horn neurons during the traveling of electrical waves in the cat spinal cord. Physiological Reports. 1(2): 1-14. e00021. , doi: 10.1002/phy2.21. ISSN 2051-817X.

Dominguez-Nicolas SM, Juarez-Aguirre R, Herrera-May AL, Garcia-Ramirez P, Figueras E, Gutierrez E, Tapia JA, Trejo A, Manjarrez E (2013).

Respiratory magnetogram detected with a MEMS device. Int. J. Med. Sci. 10(11):1445-1450. doi: 10.7150/ijms.4732. ISSN 1449-1907

Tapia JA, Trejo A, Linares P, Alva JM, Kristeva R, Manjarrez E (2013).

Reticular activating system of a central pattern generator: premovement electrical potentials. Physiological Reports. 1 (5): 1-11, e00129, doi: 10.1002/phy2.129. indexada en Pubmed

Juarez-Aguirre R, Dominguez-Nicolas SM, Manjarrez E, Tapia JA, Figueras E, Vazquez-Leal H, Aguilera-Cortes LA, Herrera-May AL (2013).

Digital signal processing by virtual instrumentation of a MEMS magnetic field sensor for biomedical applications. Sensors 13: 15068-15084.

2012

Mendez-Balbuena I, Huethe F, Schulte-Monting J, Leonhart R, Manjarrez E, Kristeva R (2012).

Corticomuscular coherence reflects interindividual differences in the state of the corticomuscular network during low-level static and dynamic forces. Cerebral Cortex. 22: 628-638.  ISSN: 1047-3211.

Mezzarane RA, Kohn AF, Couto E, Martinez L, Flores A, Manjarrez E (2012).

Absence of effects of contralateral group I muscle afferents on presynaptic inhibition of Ia terminal in humans and cats. Journal of Neurophysiology. 108: 1176-1185.

Mendez-Balbuena I, Manjarrez E, Schulte-Mönting J, Huethe F, Tapia JA, Hepp-Reymond MC, Kristeva R, (2012).

Improved sensorimotor performance via stochastic resonance.  Journal of Neuroscience. 32: 12612-12618. 

2011

Herrera-May AL, García-Ramírez PJ, Aguilera-Cortés LA, Figueras E, Martinez-Castillo J, Manjarrez E, Sauceda A, Garcia-Gonzalez L, Juarez-Aguirre R. (2011).

Mechanical design and characterization of a resonant magnetic field microsensor with linear response and high resolution. Sens Actuators A: Phys. 165: 399-409 ISSN: 0924-4247.

Herrera-May AL, García-Ramirez PJ, Aguilera-Cortés LA, Plascencia-Mora H, Garcia-Gonzalez L, Manjarrez E, Narducci M, Figueras E (2011).

Analytical Modeling for the Bending Resonant Frequency of Sensors Based on Micro-and Nanoresonators with Complex Structural Geometry. IEEE Sensors Journal. 11: 1361- 1374. ISSN: 1530-437X. 10.1109/JSEN.2010.2091403 

Tapia JA, Herrera-May AL, Garcia-Ramirez PJ, Martinez-Castillo J, Figueras E, Flores A, Manjarrez E (2011).

Sensing magnetic flux density of artificial neurons with a MEMS device. Biomedical Microdevices. 13: 303-313. ISSN: 1387-2176. 

2010

Herrera-May A, Aguilera-Cortés A, Manjarrez E, González-Palacios M (2010).

Sistemas nanoelectromecánicos: Origen, aplicaciones y desafíos. Interciencia. 35 (3): 163-170. ISSN 0378-1844. Citado en ISI Web of Science; ISI Web of Knowledge.  http://www.interciencia.org/homei.htm

2009

Cuellar CA, Tapia JA, Juárez V, Quevedo J, Linares P, Martínez L, Manjarrez E. (2009).

Propagation of sinusoidal electrical waves along the spinal cord during a fictive motor task.. Journal of Neuroscience. 29: 798-810. ISSN: 0270-6474.

Perez T, Tapia JA, Mirasso CR, Garcia-Ojalvo J, Quevedo J, Cuellar CA, Manjarrez E. (2009).

An intersegmental neuronal architecture for spinal wave propagation under deletions. Journal of Neuroscience. 29: 10254-10263. ISSN: 0270-6474.

Herrera-May AL, Aguilera-Cortés LA, García-Ramírez PJ, Manjarrez E (2009).

Resonant Magnetic Field Sensors Based On MEMS Technology.  Sensors 9: 7785-7813. ISSN 1424-8220.

2008

Toscano-Márquez B, Martínez-Martínez E, Manjarrez E, Martínez L, Mendoza-Torreblanca J, Gutiérrez-Ospina G. (2008).

Late onset muscle plasticity in the whisker pad of enucleated rats. PNAS. 105: 15973-15978. ISSN: 0027-8424

2007

Balenzuela P, Garcia-Ojalvo J, Manjarrez E, Martínez L, Mirasso CR (2007).

Ghost resonance in a pool of heterogeneous neurons. Biosystems.  89: 166-172. ISSN: 0303-2647

Manjarrez E, Balenzuela P, Garcia-Ojalvo J, Vasquez EE, Martinez L, Flores A, Mirasso CR (2007).

Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli. Biosystems. 90: 379-388. ISSN: 0303-2647

Manjarrez E, Mendez I, Martinez L, Flores A, Mirasso CR (2007).

Effects of auditory noise on the psychophysical detection of visual signals: Cross-modal stochastic resonance. Neurosci. Lett.  415: 231-236. ISSN: 0304-3940

Manjarrez E, Vazquez M, Flores A (2007).

Computing the center of mass for traveling alpha waves in the human brain. Brain Research. 1145: 239-247. ISSN: 0006-8993

Martínez L, Pérez T, Mirasso CR, Manjarrez E (2007).

Stochastic resonance in the motor system: Effects of noise on the monosynaptic reflex pathway of the cat spinal cord. Journal of Neurophysiology 97: 4007-4016. ISSN: 0022-3077

2005

Manjarrez E, Hernandez-Paxtian Z, Kohn AF (2005).

Spinal source for the synchronous fluctuations of bilateral monosynaptic reflexes in cats. Journal of Neurophysiology. 94: 3199-210. ISSN: 0022-3077.

2004

Enriquez-Denton M, Manjarrez E, Rudomin P (2004).

Persistence of PAD and presynaptic inhibition of muscle spindle afferents alter peripheral nerve crush. Brain Research 1027: 179-187. ISSN: 0006-8993

2003

Manjarrez E, Jiménez I, Rudomin P (2003).

Intersegmental synchronization of spontaneous activity of dorsal horn neurons in the cat spinal cord. Experimental Brain Research 148: 401-413. ISSN: 0014-4819.

Manjarrez E, Rojas-Piloni G, Pérez H, Méndez I, Hernández-Paxtián Z, Flores A (2003).

Stochastic resonance in the spinal cord and somatosensory cortex of the cat. Proc. SPIE 5110. Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems, (30 April 2003); doi: 10.1117/12.499488; https://doi.org/10.1117/12.499488.  Paper Number 5110  pp. 102-113. ISSN: 0277-786X http://dx.doi.org/10.1117/12.499488

Manjarrez E, Rojas-Piloni JG, Méndez I, Flores A (2003).

Stochastic resonance within the somatosensory system: effects of noise on evoked field potentials elicited by tactile stimuli. Journal of Neuroscience 23: 1997-2001. ISSN: 0270-6474.

2002

Manjarrez E, Rojas-Piloni G, Vazquez D, Flores A (2002).

Cortical neuronal ensembles driven by dorsal horn spinal neurones with spontaneous activity in the cat. Neuroscience Letters 318: 145-148. ISSN: 0304-3940

Manjarrez E, Rojas-Piloni G, Martínez L, Vázquez D, Vélez D, Méndez I, Flores A (2002).

Amplitude of somatosensory cortical evoked potentials correlated with spontaneous activity of spinal neurones in the cat. Neuroscience Letters 323: 187-190. ISSN: 0304-3940 

Manjarrez E, Diez-Martínez O, Méndez I, Flores A (2002).

Stochastic resonance in human electroencephalographic activity elicited by mechanical tactile stimuli. Neuroscience Letters 324: 213-216. ISSN: 0304-3940

Manjarrez E, Rojas-Piloni JG, Méndez I, Martínez L, Vélez D, Vázquez D, Flores A (2002).

Internal stochastic resonance in the coherence between spinal and cortical neuronal ensembles in the cat. Neuroscience Letters 326: 93-96. ISSN: 0304-3940 

Manjarrez E, Perez H, Rojas-Piloni JG, Vélez D, Martínez L, Flores A (2002).

Absence of coherence between cervical and lumbar spinal cord dorsal surface potentials in the anaesthetized cat. Neuroscience Letters 328: 37-40. ISSN: 0304-3940

2001

Manjarrez E, Rocha T, Rojas-Piloni JG, Méndez I, Vélez D, Flores A (2001).

NO donor SIN-1 potentiates monosynaptic reflexes in the cat spinal cord. NeuroReport. 12: 2667-2671. ISSN: 0959-4965

Manjarrez E, Rocha T, Rojas-Piloni JG, Méndez I, Flores A (2001).

Nitric oxide modulates spontaneous cord dorsum potentials in the cat spinal cord. Neuroscience Letters 309: 5-8.  ISSN: 0304-3940

2000

Manjarrez E, Rojas-Piloni JG, Jiménez I, Rudomin P (2000).

Modulation of synaptic transmission from segmental afferents by spontaneous activity of dorsal horn spinal neurones in the cat. Journal of Physiology (London) 529: 445-460. ISSN: 0022-3751.  (Resultado de Tesis de Doctorado) ISSN 1469-7793

Location Map





Benemérita Universidad Autónoma de Puebla
4 Sur 104 Centro Histórico C.P. 72000
Teléfono +52 (222) 229 55 00

Integrative Neurophysiology Group
Ciudad Universitaria, Building FM3
Address: Prol. de la 14 Sur 6301, Cd Universitaria, Jardines de San Manuel, 72592 Puebla, Pue.
Phone: +52 222 229 55 00
Email: eliasmanjarrez@gmail.com; elias.manjarrez@correo.buap.mx