INTEGRATIVE NEUROPHYSIOLOGY GROUP

Integrative Neurophysiology

The Integrative Neurophysiology group aims to discover emergent phenomena from neuronal systems in the brain and the spinal cord.

In particular, we analyze the electrical and hemodynamic activity of populations of neurons from the cerebral cortex, cerebellum, brainstem, and spinal cord. We integrate the study of sensory and motor systems, including neuronal systems involved in cognitive processes. We also study the complex language between neurons that includes random signaling called “neuronal noise.”

Our findings will help to generate new knowledge about fundamental mechanisms of perception, motor action, and cognition, in functional and pathological states. They also will help to design advanced prosthetic devices to augment the functional capabilities in subjects with neuronal disorders in the brain and spinal cord. 

Our experiments are performed in acute or chronic preparations in anesthetized or decerebrate animals, but also noninvasively in the human.

 

Our Methods and Heuristic Techniques

First, we explore new questions noninvasively in the human brain or the spinal cord, and then we come back to the animal preparations to examine physiological mechanisms or vice versa.

We employ emerging technologies that are perceived as capable of changing the status quo in the studies of the spinal cord or the brain functions. We also develop new neurotechnologies to open new questions in the field of emergent phenomena from the studied neuronal systems.

Some of these neurotechnologies are Optogenetics, Multielectrode Recording, Microelectromechanical Systems (MEMS), functional NIRS, transcranial random noise stimulation (tRNS), transcranial magnetic stimulation (TMS).

 

Emergent phenomena from which our group is pioneer in the Integrative-Neurophysiology field

  • The internal stochastic resonance phenomenon in the nervous system
  • The multisensory stochastic resonance phenomenon
  • The internal multisensory stochastic resonance phenomenon
  • The phenomenon of traveling waves in the spinal cord during a rhythmical motor task
  • The post-scratching locomotion phenomenon
  • The phenomenon of pre-movement electrical potentials in unconscious decerebrate animals

 

New neurotechnologies that we developed

Optogenetic noise photostimulation (ONPS), Spinal Cord Multielectrode Matrix (SCMM), Device for detection of EEG traveling waves in the human brain, Multisensory Stimulation Device (MSD).

People


Research Team

Elias Manjarrez Ph.D.

Elias Manjarrez received the B.Sc. degree in physics, the M.Sc. degree in physiology from Benemérita Universidad Autónoma de Puebla, México, and the Ph.D. degree in neuroscience from CINVESTAV-IPN, México, in 2000. He was invited professor at the Neurological Clinic, Albert-Ludwigs University of Freiburg, Germany.

Since 2001, he has been with the Institute of Physiology, Benemérita Universidad Autónoma de Puebla, México, where he is an Interdisciplinary Research Scientist and Head of the Laboratory in Integrative Neurophysiology. His areas of interest include integrative neurophysiology, stochastic resonance, traveling waves in the brain and spinal cord, spinal central pattern generators, neurophysics, mathematical modeling and biomedical applications of sensors and actuators.

Dr. Manjarrez is member of the National System of Researchers Level 3 and the Mexican Academy of Science. He obtained some competitive grants from CONACYT as “Fronteras de la Ciencia” https://www.conacyt.gob.mx/index.php/el-conacyt/desarrollo-cientifico/fronteras-de-la-ciencia and “Proyecto de Infraestructura científica y tecnológica” https://www.conacyt.gob.mx/index.php/fondos-y-apoyos/apoyos-infraestructura, and the Cátedra Marcos Moshinsky http://www.fmm.fisica.unam.mx/

 

Contact

eliasmanjarrez@gmail.com

elias.manjarrez@correo.buap.mx

+5222 2295500 Ext 7326

 

Overview

Ignacio Méndez-Balbuena Ph.D.

Ignacio Méndez-Balbuena received the B.Sc. degree in physics, the M.Sc. degree in physiological sciences from Benemérita Universidad Autónoma de Puebla, México, and the Ph.D. in physiology from Institute of Physiology, Benemérita Universidad Autónoma de Puebla, México, 2004. Post-doctorate at the Laboratory for Motor Control, Neurological Clinic, Albert-Ludwigs University of Freiburg, Germany. Currently he is Professor of the Faculty of Psychology, Benemérita Universidad Autónoma de Puebla. He is mainly interested in the development of paradigms related to experimental psycho-physiology.

Dr. Méndez Balbuena is member of the National System of Researchers Level 1.

Amira del Rayo Flores-Urbina Ph.D.

Amira del Rayo Flores received her degree in Psychology from Benemérita Universidad Autónoma de Puebla. Later, she obtained her Masters in Science in Physiological Sciences from the Institute of Physiology at the same university, and her Ph. D. degree in neuroscience from CINVESTAV-IPN, México, in 1999.

Since 2000, she has been with the Institute of Physiology, Benemérita Universidad Autónoma de Puebla, México, where she is an Interdisciplinary Research Scientist and Head of the Neurobiology Laboratory. Her areas of interest include synaptic transmission between hair cells and vestibular primary afferents, neuro development of the chicken auditory system, stochastic resonance mechanisms in synaptic transmission and integrative neurophysiology.

Dra. Flores is member of the National System of Researchers Level 2.

Master Students

Anler Diaz Gonzalez

Luis Enrique Martínez Villavicencio

Lisset Bueno Figueredo

Ivanna Fontirroche Reyes

Martín Alberto Amador Manilla

PhD Students

Anai Gonzalez-Ramirez

Anai Gonzalez-Ramirez, BSc, received her degree in Biomedical Research from Benemérita Universidad Autónoma de Puebla, in 2017. She is currently studying her Masters in Science in Physiological Sciences at Institute of Physiology. She made an internship at Dormunt University, Germany in 2018 in the laboratory of Dr. Ruge and Dr. Trenado. Gonzalez-Ramirez currently is working in her MSc thesis examining neural variability in EEG evoked potentials in humans.

Jorge Gutierrez

Jorge Gutierrez, received his degree in biomedical Research from Benemérita Universidad Autónoma de Puebla, in 2018. He is currently studying his Master in Physiological Sciences at Institute of Physiology. He is characterizing electrical activity of single neurons from the cat spinal cord associated with the phenomenon of spinal traveling waves during scratching and locomotion.

Collaborative Network

International collaborations

 

 

 

National collaborations

 

 



Patents Granted

  • Patent granted by Mexican Institute of Industrial Property IMPI #351753, “Title: Trayectómetro de señales eléctricas cerebrales”. Patent granted from October 18th 2017 to September 28th 2032.
     
  • Patent granted by Mexican Institute of Industrial Property IMPI #357897, Title: Dispositivo neuromimético del dedo humano controlado por antiresonancia estocástica”. Patent granted from July 4th 2017 to September 28th 2032.
     
  • Patent granted by Mexican Institute of Industrial Property IMPI #359610, Title: Multielectrodo de superficie motorizado de 32 canales”. Patent granted from September 14th 2017 to September 28th 2032.
     
  • Patent granted by IMPI 357897 “Dispositivo neuromimético del dedo humano controlado por antiresonancia estocástica” (4th July  2018)
     
  • Patent granted by IMPI 378551 “Sistema portátil para la obtención de imágenes cerebrales y espinales por transiluminación inalámbrica” (November 5th 2020)

Publications

2023

DeLuna-Castruita, A, Lizarraga-Cortes, V, Flores, A, Manjarrez, E.

(2023) ADHD Adults Show Lower Interindividual Similarity in Ex-Gaussian Reaction Time Vectors for Congruent Stimuli Compared to Control Peers. Journal of attention disorders, 10870547231214966. Advance online publication. https://doi.org/10.1177/10870547231214966. ISSN electrónico: 1662453X

Manjarrez E, Curia G, Stecina K, Lopez Valdes A.

(2023) Editorial: Bridging the gap between integrative neuroscience and translational neuroscience. Front Integr Neurosci. 17:1296701. doi: 10.3389/fnint.2023.1296701. ISSN electrónico: 1662-5161.

Manjarrez E, Campana G, Mirasso C, Battelli L.

(2023) Editorial: Insights into the mechanisms of transcranial electrical stimulation. Front Neurosci. 17:1286239. doi: 10.3389/fnins.2023.1286239. ISSN electrónico: 1662453X

Ramírez, A., Monjaraz, E., Manjarrez, E., Moyaho, A., Cebada, J., & Flores, A.

(2023). Pharmacological characterization and differential expression of NMDA receptor subunits in the chicken vestibular system during development. Synapse (New York, N.Y.), 77(1), e22252. https://doi.org/10.1002/syn.22252. ISSN: 1648-9144

2022

Fragoso A, Martínez B, Ceballos-Villegas ME, Herrera E, Saldaña JJ, Gutiérrez-Lozano AL, Manjarrez E, Lomelí J.

(2022) Absence of Neuroplastic Changes in the Bilateral H-Reflex Amplitude following Spinal Manipulation with Activator IV. Medicina. 2022; 58(11):1521. https://doi.org/10.3390/medicina58111521. ISSN: 1648-9144

Curia G, Estrada-Camarena E, Manjarrez E and Mizuno H.

(2022) Editorial: In vivo investigations on neurological disorders: From traditional approaches to forefront technologies. Front. Neurosci. 16:1052089. doi: 10.3389/fnins.2022.1052089. ISSN electrónico: 1662453X

Herrera-Murillo M.A, Treviño M, Manjarrez E.

(2022) Random noise stimulation in the treatment of patients with neurological disorders. Neural Regeneration Res. Neural Regen Res. 2022 Dec; 17(12):2557-2562. doi: 10.4103/1673-5374.339474. ISSN impreso: 16735374

Treviño M, Manjarrez E.

(2022) Balanced Expression of G Protein-coupled Receptor Subtypes in the Mouse, Macaque, and Human Cerebral Cortex. Neuroscience. Apr 1; 487:107-119. doi: 10.1016/j.neuroscience.2022.01.028. ISSN: 0306-4522 .

2021

Dominguez-Nicolas SM, Manjarrez E.

(2021) Low-field thoracic magnetic stimulation increases peripheral oxygen saturation levels in coronavirus disease (COVID-19) patients: A single-blind, sham-controlled, crossover study. Medicine (Baltimore). Oct 8; 100(40):e27444. doi: 10.1097/MD.0000000000027444. ISSN: 1536-5964

Tapia JA, Reid A, Reid J, Dominguez-Nicolas SM, Manjarrez E.

(2021) Modeling Post-Scratching Locomotion with Two Rhythm Generators and a Shared Pattern Formation. Biology (Basel) Jul 14; 10(7):663. doi: 10.3390/biology10070663.

Mabil P, Huidobro N, Flores A, Manjarrez E

(2021) Potential role of noise to improve intracortical microstimulation in tactile neuroprostheses. Neural Regen Res. 16: 1533-1534. ISSN: 16735374. DOI: 10.4103/1673-5374.303018.

Méndez-Reyes JM, López-Huerta F, Manjarrez E

(2021) Tratamientos para mitigar el congelamiento de la marcha en la enfermedad de Parkinson: Treatments for freezing of gait in Parkinson’s disease. Revista Internacional de Investigación e Innovación Tecnológica Año: 9, No. 51, 76-86. ISSN: 2007-9753, Latindex Folio: 23614.

2020

Manjarrez E, Olmos R, Cedillo L, Salazar-Ibarguen HA

(2020) Stochastic filtrate of essential workers to reactivate the world economy safely. Front. Phys. 8:371. https://doi.org/10.3389/fphy.2020.00371. ISSN: 2296-424X

Mabil P, Huidobro N, Torres-Ramirez O, Flores-Hernandez J, Flores A, Gutierrez R, Manjarrez E.

(2020) Noisy Light Augments the Na + Current in Somatosensory Pyramidal Neurons of Optogenetic Transgenic Mice. Front Neurosci. 14:490. doi: 10.3389/fnins.2020.00490. ISSN: 1662453X

Huidobro N, Gutierrez-Gomez A, Gutierrez J, Zea I, Mendez-Balbuena I, Flores A, Trenado C, Manjarrez E.

(2020) Augmenting Global Coherence in EEG Signals With Binaural or Monaural Noises. Brain Topogr. 33(4):461-476. doi: 10.1007/s10548-020-00774-5. ISSN: 0896-0267

Hernández-Carballo G, Ruíz-Luna EA, López-López G, Manjarrez E, Flores-Hernández J.

(2020) Changes in Serotonin Modulation of Glutamate Currents in Pyramidal Offspring Cells of Rats Treated With 5-MT During Gestation. Brain Sci. 10(4): 221. doi: 10.3390/brainsci10040221.

Moreno-Castillo M, Meza R, Romero-Vaca J, Huidobro N, Méndez-Fernández A, Martínez-Castillo J, Mabil P, Flores A and Manjarrez E 

(2020) The Hemodynamic Mass Action of a Central Pattern Generator. Front. Neurosci. 14:38. doi: 10.3389/fnins.2020.00038

Méndez-Fernández A, Moreno-Castillo M, Huidobro N, Flores A, Manjarrez E

 (2020) Afterdischarges of Spinal Interneurons Following a Brief High-Frequency Stimulation of Ia Afferents in the Cat. Front Integr Neurosci. 13:75. doi: 10.3389/fnint.2019.00075

2019

Trenado C, González-Ramírez A, Lizárraga-Cortés V, Pedroarena Leal N, Manjarrez E, Ruge D. 

(2019) The Potential of Trial-by-Trial Variabilities of Ongoing-EEG, Evoked Potentials, Event Related Potentials and fMRI as Diagnostic Markers for Neuropsychiatric Disorders. Front Neurosci. 12:850. doi: 10.3389/fnins.2018.00850.

Meza R, Huidobro N, Moreno-Castillo M, Mendez-Fernandez A, Flores-Hernandez J, Flores A, Manjarrez E.

(2019) Resetting the Respiratory Rhythm with a Spinal Central Pattern Generator. 6(2). Pii: eNeuro 0116-19.2019. doi: 10.1523/eneuro.0116-19.2019

Remedios L, Mabil P, Flores-Hernández J, Torres-Ramírez O, Huidobro N, Castro G, Cervantes L, Tapia JA, De la Torre Valdovinos B, Manjarrez E (2019)

Effects of Short-Term Random Noise Electrical Stimulation on Dissociated Pyramidal Neurons from the Cerebral Cortex. Neuroscience. 404:371-386.

2018

Huidobro N, De la Torre-Valdovinos B, Mendez A, Treviño M, Arias-Carion O, Chavez F, Gutierrez R, Manjarrez E (2018).

Optogenetic noise-photostimulation on the brain increases somatosensory spike firing responses. Neurosci Lett. 664: 51-57.

Cuellar CA, De La Torre Valdovinos B, Huidobro N, Delgado-Lezama R, Ornelas-Kobayashi R, Manjarrez E (2018)

The Spinal Neurons Exhibit an ON-OFF and OFF-ON Firing Activity Around the Onset of Fictive Scratching Episodes in the Cat. Front Cell Neurosci. 12:68. doi: 10.3389/fncel.2018.00068.

Mendez-Balbuena I, Arrieta P, Huidobro N, Flores A, Lemuz-Lopez R, Trenado C, Manjarrez E (2018).

Augmenting EEG-global-coherence with auditory and visual noise: Multisensory internal stochastic resonance. Medicine (Baltimore). 97(35): e12008. doi: 10.1097/MD.0000000000012008.

2017

Huidobro N, Mendez-Fernandez A, Mendez-Balbuena I, Gutierrez R, Kristeva R, Manjarrez E (2017).

Brownian optogenetic-noise-photostimulation on the brain amplifies somatosensory-evoked field potentials. Front Neurosci. 11: 464. https://doi.org/10.3389/fnins.2017.00464

Ceballos-Villegas ME, Saldaña-Mena JJ, Gutierrez-Lozano AL, Sepúlveda-Cañamar J, Huidobro N, Manjarrez E, Lomeli J. (2017).

The complexity of H-wave amplitude fluctuations and their bilateral cross-covariance are modified according to the previous fitness history of young subjects under track training. Frontiers in human Neurosci. 11: 530

Canto-Bustos M, Loeza-Alcocer E, Cuellar CA, Osuna P, Elias-Viñas D, Granados-Soto V, Manjarrez E, Felix R, Delgado-Lezama R. (2017).

Tonically Active α5GABAA Receptors Reduce Motoneuron Excitability and Decrease the Monosynaptic Reflex. Front Cell Neurosci. 11:283.

2016

Franco LM, Beltrán JQ, Tapia JA, Ortiz F, Manjarrez E, Gutiérrez R (2016).

Differential frequency-dependent antidromic resonance of the Schaffer collaterals and mossy fibers. Brain Struct Funct. 221(4):1793-1807

Flores A, Manilla S, Huidobro N, De la Torre-Valdovinos B, Kristeva R, Mendez-Balbuena I, Galindo F, Treviño M, Manjarrez E (2016).

Stochastic resonance in the synaptic transmission between hair cells and vestibular afferents in development. Neuroscience. 322: 416-429.

Treviño M, De la Torre-Valdovinos B, Manjarrez E (2016).

Noise improves visual motion discrimination via a stochastic resonance-like phenomenon. Front Hum Neurosci. 10:  572.  http://dx.doi.org/10.3389/fnhum.2016.00572

2015

Mendez-Balbuena I, Huidobro N, Silva M, Flores A, Trenado C, Quintanar L, Arias Carrion O, Kristeva R, Manjarrez E (2015).

Effect of mechanical tactile noise on the amplitude of visual evoked potentials: Multisensory stochastic resonance. Journal of Neurophysiology. 114: 2132-2143.

Trejo A, Tapia JA, De la Torre Valdovinos B, Huidobro N, Flores G, Flores-Hernandez J, Flores A, Manjarrez E (2015).

Transition of pattern generation: The phenomenon of post-scratching locomotion. Neuroscience. 288: 156-166.

2014

Trenado C, Mikulic A, Manjarrez E, Mendez-Balbuena I, Schulte-Monting J, Huethe F, Hepp-Reymond MC, Kristeva R (2014).

Broad-band Gaussian noise is most effective in improving motor performance and is most pleasant. Frontiers in Human Neuroscience. 8: 22. http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00022/abstract

Cuellar CA, Trejo A, Linares P, Delgado-Lezama R, Jiménez-Estrada I, Abyazova LM, Baltina TV, Manjarrez E.(2014).

Spinal neurons bursting in phase with fictive scratching are not related to spontaneous cord dorsum potentials. Neuroscience. 266: 66-79

Trenado C, Mendez-Balbuena I, Manjarrez E, Huethe F, Schulte-Monting J, Feige B, Hepp-Reymond MC, Kristeva R (2014).

Enhanced corticomuscular coherence by external stochastic noise. Front. Hum. Neurosci. 8: 325. http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00325/abstract

Romero-Pimentel AL, Vazquez-Roque RA, Camacho-Abrego I, Hoffman KL, Linares P, Flores G, Manjarrez E (2014).

Histological correlates of N40 auditory evoked potentials in adult rats after neonatal ventral hippocampal lesion: animal model of schizophrenia. Schizophrenia Research. 159(2–3): 450–457.  doi:10.1016/j.schres.2014.09.009

Herrera-May AL, Tapia JA, Dominguez-Nicolas SM, Juarez-Aguirre R, Gutierrez-D EA, Flores A, Figueras E, Manjarrez E (2014).

Improved detection of magnetic signals by a MEMS sensor using stochastic resonance. PlosOne 9(10): e109534. doi:10.1371/journal.pone.0109534

Trenado C, Amtage F, Huethe F, Schulte-Monting J, Mendez-Balbuena I, Baker SN, Baker M, Hepp-Reymond MC, Manjarrez E, Kristeva R (2014).

Suppression of Enhanced Physiological Tremor via Stochastic Noise: Initial Observations. PlosOne 9(11): e112782. doi:10.1371/journal.pone.0112782

Martinez-Silva L, Manjarrez E, Gutierrez-Ospina G, Quevedo JN (2014).

Electrophysiological representation of scratching CPG activity in the cerebellum. PlosOne 9(10): e109936. doi:10.1371/journal.pone.0109936. http://www.ncbi.nlm.nih.gov/pubmed/25350378

2013

Kato H, Cuellar CA, Delgado-Lezama R, Rudomin P, Jimenez-Estrada I, Manjarrez E, Mirasso CR (2013).

Modeling zero-lag synchronization of dorsal horn neurons during the traveling of electrical waves in the cat spinal cord. Physiological Reports. 1(2): 1-14. e00021. , doi: 10.1002/phy2.21. ISSN 2051-817X.

Dominguez-Nicolas SM, Juarez-Aguirre R, Herrera-May AL, Garcia-Ramirez P, Figueras E, Gutierrez E, Tapia JA, Trejo A, Manjarrez E (2013).

Respiratory magnetogram detected with a MEMS device. Int. J. Med. Sci. 10(11):1445-1450. doi: 10.7150/ijms.4732. ISSN 1449-1907

Tapia JA, Trejo A, Linares P, Alva JM, Kristeva R, Manjarrez E (2013).

Reticular activating system of a central pattern generator: premovement electrical potentials. Physiological Reports. 1 (5): 1-11, e00129, doi: 10.1002/phy2.129. indexada en Pubmed

Juarez-Aguirre R, Dominguez-Nicolas SM, Manjarrez E, Tapia JA, Figueras E, Vazquez-Leal H, Aguilera-Cortes LA, Herrera-May AL (2013).

Digital signal processing by virtual instrumentation of a MEMS magnetic field sensor for biomedical applications. Sensors 13: 15068-15084.

2012

Mendez-Balbuena I, Huethe F, Schulte-Monting J, Leonhart R, Manjarrez E, Kristeva R (2012).

Corticomuscular coherence reflects interindividual differences in the state of the corticomuscular network during low-level static and dynamic forces. Cerebral Cortex. 22: 628-638.  ISSN: 1047-3211.

Mezzarane RA, Kohn AF, Couto E, Martinez L, Flores A, Manjarrez E (2012).

Absence of effects of contralateral group I muscle afferents on presynaptic inhibition of Ia terminal in humans and cats. Journal of Neurophysiology. 108: 1176-1185.

Mendez-Balbuena I, Manjarrez E, Schulte-Mönting J, Huethe F, Tapia JA, Hepp-Reymond MC, Kristeva R, (2012).

Improved sensorimotor performance via stochastic resonance.  Journal of Neuroscience. 32: 12612-12618. 

2011

Herrera-May AL, García-Ramírez PJ, Aguilera-Cortés LA, Figueras E, Martinez-Castillo J, Manjarrez E, Sauceda A, Garcia-Gonzalez L, Juarez-Aguirre R. (2011).

Mechanical design and characterization of a resonant magnetic field microsensor with linear response and high resolution. Sens Actuators A: Phys. 165: 399-409 ISSN: 0924-4247.

Herrera-May AL, García-Ramirez PJ, Aguilera-Cortés LA, Plascencia-Mora H, Garcia-Gonzalez L, Manjarrez E, Narducci M, Figueras E (2011).

Analytical Modeling for the Bending Resonant Frequency of Sensors Based on Micro-and Nanoresonators with Complex Structural Geometry. IEEE Sensors Journal. 11: 1361- 1374. ISSN: 1530-437X. 10.1109/JSEN.2010.2091403 

Tapia JA, Herrera-May AL, Garcia-Ramirez PJ, Martinez-Castillo J, Figueras E, Flores A, Manjarrez E (2011).

Sensing magnetic flux density of artificial neurons with a MEMS device. Biomedical Microdevices. 13: 303-313. ISSN: 1387-2176. 

2010

Herrera-May A, Aguilera-Cortés A, Manjarrez E, González-Palacios M (2010).

Sistemas nanoelectromecánicos: Origen, aplicaciones y desafíos. Interciencia. 35 (3): 163-170. ISSN 0378-1844. Citado en ISI Web of Science; ISI Web of Knowledge.  http://www.interciencia.org/homei.htm

2009

Cuellar CA, Tapia JA, Juárez V, Quevedo J, Linares P, Martínez L, Manjarrez E. (2009).

Propagation of sinusoidal electrical waves along the spinal cord during a fictive motor task.. Journal of Neuroscience. 29: 798-810. ISSN: 0270-6474.

Perez T, Tapia JA, Mirasso CR, Garcia-Ojalvo J, Quevedo J, Cuellar CA, Manjarrez E. (2009).

An intersegmental neuronal architecture for spinal wave propagation under deletions. Journal of Neuroscience. 29: 10254-10263. ISSN: 0270-6474.

Herrera-May AL, Aguilera-Cortés LA, García-Ramírez PJ, Manjarrez E (2009).

Resonant Magnetic Field Sensors Based On MEMS Technology.  Sensors 9: 7785-7813. ISSN 1424-8220.

2008

Toscano-Márquez B, Martínez-Martínez E, Manjarrez E, Martínez L, Mendoza-Torreblanca J, Gutiérrez-Ospina G. (2008).

Late onset muscle plasticity in the whisker pad of enucleated rats. PNAS. 105: 15973-15978. ISSN: 0027-8424

2007

Balenzuela P, Garcia-Ojalvo J, Manjarrez E, Martínez L, Mirasso CR (2007).

Ghost resonance in a pool of heterogeneous neurons. Biosystems.  89: 166-172. ISSN: 0303-2647

Manjarrez E, Balenzuela P, Garcia-Ojalvo J, Vasquez EE, Martinez L, Flores A, Mirasso CR (2007).

Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli. Biosystems. 90: 379-388. ISSN: 0303-2647

Manjarrez E, Mendez I, Martinez L, Flores A, Mirasso CR (2007).

Effects of auditory noise on the psychophysical detection of visual signals: Cross-modal stochastic resonance. Neurosci. Lett.  415: 231-236. ISSN: 0304-3940

Manjarrez E, Vazquez M, Flores A (2007).

Computing the center of mass for traveling alpha waves in the human brain. Brain Research. 1145: 239-247. ISSN: 0006-8993

Martínez L, Pérez T, Mirasso CR, Manjarrez E (2007).

Stochastic resonance in the motor system: Effects of noise on the monosynaptic reflex pathway of the cat spinal cord. Journal of Neurophysiology 97: 4007-4016. ISSN: 0022-3077

2005

Manjarrez E, Hernandez-Paxtian Z, Kohn AF (2005).

Spinal source for the synchronous fluctuations of bilateral monosynaptic reflexes in cats. Journal of Neurophysiology. 94: 3199-210. ISSN: 0022-3077.

2004

Enriquez-Denton M, Manjarrez E, Rudomin P (2004).

Persistence of PAD and presynaptic inhibition of muscle spindle afferents alter peripheral nerve crush. Brain Research 1027: 179-187. ISSN: 0006-8993

2003

Manjarrez E, Jiménez I, Rudomin P (2003).

Intersegmental synchronization of spontaneous activity of dorsal horn neurons in the cat spinal cord. Experimental Brain Research 148: 401-413. ISSN: 0014-4819.

Manjarrez E, Rojas-Piloni G, Pérez H, Méndez I, Hernández-Paxtián Z, Flores A (2003).

Stochastic resonance in the spinal cord and somatosensory cortex of the cat. Proc. SPIE 5110. Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems, (30 April 2003); doi: 10.1117/12.499488; https://doi.org/10.1117/12.499488.  Paper Number 5110  pp. 102-113. ISSN: 0277-786X http://dx.doi.org/10.1117/12.499488

Manjarrez E, Rojas-Piloni JG, Méndez I, Flores A (2003).

Stochastic resonance within the somatosensory system: effects of noise on evoked field potentials elicited by tactile stimuli. Journal of Neuroscience 23: 1997-2001. ISSN: 0270-6474.

2002

Manjarrez E, Rojas-Piloni G, Vazquez D, Flores A (2002).

Cortical neuronal ensembles driven by dorsal horn spinal neurones with spontaneous activity in the cat. Neuroscience Letters 318: 145-148. ISSN: 0304-3940

Manjarrez E, Rojas-Piloni G, Martínez L, Vázquez D, Vélez D, Méndez I, Flores A (2002).

Amplitude of somatosensory cortical evoked potentials correlated with spontaneous activity of spinal neurones in the cat. Neuroscience Letters 323: 187-190. ISSN: 0304-3940 

Manjarrez E, Diez-Martínez O, Méndez I, Flores A (2002).

Stochastic resonance in human electroencephalographic activity elicited by mechanical tactile stimuli. Neuroscience Letters 324: 213-216. ISSN: 0304-3940

Manjarrez E, Rojas-Piloni JG, Méndez I, Martínez L, Vélez D, Vázquez D, Flores A (2002).

Internal stochastic resonance in the coherence between spinal and cortical neuronal ensembles in the cat. Neuroscience Letters 326: 93-96. ISSN: 0304-3940 

Manjarrez E, Perez H, Rojas-Piloni JG, Vélez D, Martínez L, Flores A (2002).

Absence of coherence between cervical and lumbar spinal cord dorsal surface potentials in the anaesthetized cat. Neuroscience Letters 328: 37-40. ISSN: 0304-3940

2001

Manjarrez E, Rocha T, Rojas-Piloni JG, Méndez I, Vélez D, Flores A (2001).

NO donor SIN-1 potentiates monosynaptic reflexes in the cat spinal cord. NeuroReport. 12: 2667-2671. ISSN: 0959-4965

Manjarrez E, Rocha T, Rojas-Piloni JG, Méndez I, Flores A (2001).

Nitric oxide modulates spontaneous cord dorsum potentials in the cat spinal cord. Neuroscience Letters 309: 5-8.  ISSN: 0304-3940

2000

Manjarrez E, Rojas-Piloni JG, Jiménez I, Rudomin P (2000).

Modulation of synaptic transmission from segmental afferents by spontaneous activity of dorsal horn spinal neurones in the cat. Journal of Physiology (London) 529: 445-460. ISSN: 0022-3751.  (Resultado de Tesis de Doctorado) ISSN 1469-7793

Proceedings articles

Mabil-Espinosa P, Martinez-Castillo J, Manjarrez E, Delgado-Alvarado E, Herrera-May AL, EspinozaMaza JJ, Mendoza-Barron G, Roman-Jara S (2023) A Functional Photoplethysmography Device Measuring Changes in the Auditory Cortex During the Application of Emotional Sound. IEEE International Conference on Engineering Veracruz (ICEV), Boca del Río, Veracruz, Mexico, 2023, pp. 1-5, doi: 10.1109/ICEV59168.2023.10329693.

Lara-Lopez DA, Martinez-Castillo J, Delgado-Alvarado E, Morales-Gonzalez EA, Espinoza-Maza JJ, Mendoza-Barron G, Domínguez-Márquez J, Mabil-Espinosa P, Manjarrez E (2022) Changes in Measurement of Direct Current Photoplethysmography signals with a Wireless Transillumination System. 2022 IEEE International Conference on Engineering Veracruz (ICEV), 2022, pp. 1-5, doi: 10.1109/ICEV56253.2022.9959184. ISBN: 978-1-6654-5213-7

D. A. Lara-López et al., "Wireless System Design for Direct Current Photoplethysmography," 2021 IEEE International Conference on Engineering Veracruz (ICEV), 2021, pp. 1-5, doi: 10.1109/ICEV52951.2021.9632627. Electronic ISBN: 978-1-6654-4548-1 (Conference Proceedings for IEEE Xplore)

Angel-Vargas D, Herrera-May AL, Martinez-Castilo J, Salas-Rodriguez S, Lopez-Huerta F, MoralesGonzalez EA, Manjarrez-Lopez E (2019) "Matrix array of CMOS photodetectors for brain transillumination," 2019 IEEE International Conference on Engineering Veracruz (ICEV), Year: 2019,Volume: 1, pp. 1-5, Conference Paper, doi: 10.1109/ICEV.2019.8920652. Electronic ISBN:978- 1-7281-3304-1

Location Map





Benemérita Universidad Autónoma de Puebla
4 Sur 104 Centro Histórico C.P. 72000
Teléfono +52 (222) 229 55 00

Integrative Neurophysiology Group
Ciudad Universitaria, Building FM3
Address: Prol. de la 14 Sur 6301, Cd Universitaria, Jardines de San Manuel, 72592 Puebla, Pue.
Phone: +52 222 229 55 00
Email: eliasmanjarrez@gmail.com; elias.manjarrez@correo.buap.mx